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Fee-for-Service Rates

The UC Davis/NIH NeuroMab Facility has expanded its high-quality antibody services on a fee-for-service basis to the broader biomedical research community, including scientists whose target priorities differ from those funded by our grants.  Our new aims are three-fold:

1) to extend our unique multi-step neuroscience-based screening approach to work on non-NINDS-prioritized neuroscience targets that are suggested by academic and commercial clients;

2) to apply a similar multi-step target-specific screening approach to non-neuroscience targets that are important to our academic and commercial colleagues; and

3) to validate existing commercial antibodies for utility in standard biochemical and immunohistochemical analyses against mammalian brain.

Overall costs for typical projects are:

Brief project description

UCD Campus Recharge Rate

Non-UCD Academic Rate

Non-UCD Commercial Rate

Non-brain-justified target with client-provided immunogen and cell IF screens only

$4,307

$5,761

$11,522

Non-brain-justified target with immunogen production and cell IF screens only

$7,974

$10,664

$21,328

Brain-justified target with client-provided immunogen, cell IF screens, tissue IB screens and tissue IHC screens

$8,442

$11,290

$22,581

Brain-justified target with immunogen production, cell IF screens, tissue IB screens and tissue IHC screens

$12,109

$16,193

$32,387

Our detailed services and rates are listed below and in an Excel worksheet to help you generate a custom price quote.

Service

Brief Description UCD Campus Recharge Rate Non-UCD Academic Rate Non-UCD Commercial Rate
General oversight and strategy development (all targets) Hourly rate for client meetings, development of screening strategy and drafting reports

$116 per hour

$155 per hour $310 per hour
General oversight and strategy development (brain targets) Hourly rate for client meetings, development of screening strategy and drafting reports $91 per hour $120 per hour $241 per hour
Immunogen design and production Immunogen design, cloning, screening, test expression, large-scale preparation and quality control for single target $3,667 $4,903 $9,806
Mouse immunizations and serum collection Immunization of two mice for single target and tailbleed collection according to 30-day standard operating procedure $331 $443 $886
Serum testing One round of tailbleed testing for single target by cell immunofluorescence (IF) and tissue immunoblot (IB) $160 $214 $428
Fusion, cell culture and antibody collection Electrofusion into 32 96-well plates (≈3000 antibodies) followed by cell expansion, supe collection and cell freezing for ≈96 antibodies then ≈24 antibodies (or 5 x 5 monoclonal subclones) $1,832 $2,450 $4,900
ELISA, FLISA and miscellaneous work ELISA/FLISA protocol using BioCel automated liquid-handling robot and data analysis for ≈3000 antibodies, then ≈96 antibodies, then ≈24 antibodies (or 5 x 5 subclones) $1,170 $1,565 $3,130
Cell IF screening or validation Plating and transfecting cells, cell IF protocol and data analysis for ≈96 antibodies, then ≈24 antibodies (or 5 x 5 subclones) $698 $934 $1,868
Tissue IB screening or validation (1-24 samples) Gel running, tissue IB protocol and data analysis for a batch of ≈24 samples (e.g. 5 x 5 subclones) $266 $356 $712
Tissue IB screening or validation (25-96 samples) Gel running, tissue IB protocol and data analysis for multiple batches of samples (e.g. 24 antibodies x 2 dilutions) $706 $944 $1,888
Brain immunohistochemistry (IHC) screening or validation (1-24 samples) Rat perfusions, brain IHC protocol and data analysis for a batch of ≈24 samples (e.g. 5 x 5 subclones) $985 $1,317 $2,634
Brain IHC screening or validation (25-48 samples) Rat perfusions, brain IHC protocol and data analysis for two batches of ≈24 samples (e.g. 24 antibodies x 2 dilutions) $1,342 $1,795 $3,590
Brain IHC screening or validation (49-96 samples) Rat perfusions, brain IHC protocol and data analysis for multiple batches of samples (e.g. 48 antibodies x 2 dilutions) $1,730 $2,314 $4,628
Ascites production prep work Cell culture and preparation of single antibody for commercial vendor $175 $234 $468

Please contact us if you have any questions.  We welcome the opportunity to use our technology, time and expertise to benefit additional biomedical researchers by generating reliable mAbs that might not otherwise be available and by performing comprehensive experimental verifications that save countless investigators the time, money and effort of attempting to use expensive yet suboptimal reagents in their work.

 

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