Note that all NeuroMabs have tested positive by ELISA versus the synthetic peptide or recombinant protein immunogen (and in the case of modification-specific NeuroMabs, to the modified and not unmodified synthetic peptide immunogen).

T: specific reaction to transfected cells expressing target (by immunofluorescence staining and/or immunoblot)

Br-IB: single immunoreactive band of expected molecular characteristics on brain immunoblots

Br-IHC: expected immunoperoxidase-diaminobenzidine/immunofluorescence staining pattern on brain sections

KO: knockout validated in mouse brain (by immunoblot and/or immunohistochemistry)

  = validation pass

= validation fail

ND = not determined

NA = not applicable (e.g., target not expressed in brain)