The UC Davis/NIH NeuroMab Facility is accepting suggestions as to future NeuroMab targets.

Requestors should supply the UC Davis/NIH NeuroMab Facility with:

• a scientific justification as to the biological importance of the target molecule, the importance of these reagents to the national neuroscience community, and the availability and suitability of existing polyclonal and/or monoclonal antibodies.

• a list of reagents (synthetic peptides, fusions proteins, full-length cDNAs for transfection in mammalian cells, samples from knockout mice) that will be made available to the NeuroMab staff to facilitate the development and characterization of these NeuroMabs.

• detailed information on the expression pattern of the target molecule in mammalian brain. Especially crucial is information on its developmental pattern of expression, and its regional, cellular and subcellular distribution in adult brain. Any information for expression in rat, which is the system used for NeuroMab screening and validation, is especially helpful. Include relevant references if possible.

Submit this information to the UC Davis/NIH NeuroMab Facility here by clicking the 'Submit' button so that an automatic e-mail gets sent to neuromab@ucdavis.edu. The NeuroMab advisory board, acting in concert with program officials from NINDS and NIMH, will then prioritize the request in the NeuroMab queue. Upon completion of a project, any resulting NeuroMabs will then be added to the catalog and made freely available to the research community at low cost.  Note that all hybridomas and mAbs developed by the UC Davis/NIH NeuroMab Facility are the property of the Regents of the University of California.

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